We are a synthetic chemistry group which uses a combination of organofluorine chemistry, catalysis and peptide chemistry to tackle a variety of chemical challenges.
One of the main areas we are interested in is the development of new synthetic methodologies. Particularly in the areas of organofluorine chemistry and late-stage diversification of biologically relevant scaffolds. We try to develop new methods which are simple to perform, use commercially available reagents and which can be carried out under mild conditions.
Recently we have been focusing on developing new methods of deoxyfluorination and the application of in-situ acyl fluoride formation to coupling processes. In addition we also have an active research program in using metal-based catalysis in combination with peptides to deliver new catalysis platforms for applications in green chemistry.